Best known for playing Dr. Robert Chase in ‘House M.D.’ (2004–2012), Lieutenant Matthew Casey in ‘Chicago Fire’ (2012–2022), and Billy Kennedy in the Australian soap ‘Neighbours’ (1994–2000).
Films
- Death in LoveYoung Man2008
- The Girl Who Invented KissingJimmy2006
- MercuryMitch2005
- Uptown GirlsNeal2003
- Swimming UpstreamTony Fingleton2003
TV shows
- Chicago FireLt. Matthew Casey2012–2022
- Chicago P.D.Lt. Matthew Casey (guest)2014
- Chicago MedLt. Matthew Casey (guest)2015
- House M.D.Dr. Robert Chase2004–2012
- Blue HeelersLee Cruickshank (guest)1999
- NeighboursBilly Kennedy1994–2000
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About Jesse Spencer
Jesse Spencer is an Australian actor who rose to fame as Dr. Robert Chase in the medical drama House (2004–2012) and as Lieutenant Matthew Casey in the NBC drama Chicago Fire (2012–2022). He began his career as a child actor on the long-running soap opera Neighbours, where he played Billy Kennedy, and has also appeared in several independent films.
FAQs
What is Jesse Spencer’s most famous role?
He is best known for playing Dr. Robert Chase in the medical drama ‘House M.D.’ (2004–2012) and Lieutenant Matthew Casey in ‘Chicago Fire’ (2012–2022).
Is Jesse Spencer still on Chicago Fire?
He left as a regular at the end of Season 10 (2022) but has made guest appearances in later seasons. His character’s storylines continue to be referenced.
What awards has Jesse Spencer won?
He won the Logie Award for Most Popular New Talent for his role in ‘Neighbours’ (1995) and has received multiple nominations for his work on ‘House’ and ‘Chicago Fire’.
Sources & where to watch: IMDb · Wikipedia · Where to watch (JustWatch UK) · Updated June 2026