Angie Harmon stars as Detective Jane Rizzoli and Sasha Alexander as Dr. Maura Isles in ‘Rizzoli and Isles‘, a crime drama based on Tess Gerritsen’s novels.
Main cast
- Detective Jane RizzoliAngie HarmonMain
- Dr. Maura IslesSasha AlexanderMain
Supporting cast
- Detective Vince KorsakBruce McGillSupp
- Detective Barry FrostLee Thompson Young1–4Supp
- Frankie Rizzoli Jr.Jordan BridgesSupp
- Angela RizzoliLorraine BraccoSupp
- Lieutenant Sean CavanaughBrian GoodmanSupp
- Detective Nina HolidayIdara Victor5–7Supp
- Susie ChangTina HuangSupp
Guest & voice
- Detective Darren CroweColin Egglesfield1Guest
- Paddy DoyleBilly Burke2–3Guest
- Dr. Hope MartinSharon Lawrence1–2Guest
- Sophie RizzoliAlysia Reiner4Guest
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About this cast
Rizzoli and Isles is a crime drama that aired for seven seasons on TNT, following the unlikely partnership between tough Boston detective Jane Rizzoli and refined medical examiner Dr. Maura Isles. The series blends procedural cases with the duo’s strong personal bond and family dynamics.
FAQs
Who plays Jane Rizzoli in Rizzoli and Isles?
Jane Rizzoli is played by American actress Angie Harmon.
Who plays Maura Isles in Rizzoli and Isles?
Dr. Maura Isles is played by Macedonian-American actress Sasha Alexander.
Is Rizzoli and Isles based on a book series?
Yes, the series is based on the Rizzoli & Isles novels by Tess Gerritsen, though the TV show takes many liberties with the source material.
How many seasons of Rizzoli and Isles are there?
Rizzoli and Isles ran for seven seasons, airing 105 episodes from 2010 to 2016.
Where can I watch Rizzoli and Isles in the UK?
In the UK, the series is available to stream on Amazon Prime Video, and previously aired on Alibi.
Sources & where to watch: IMDb · Wikipedia · Where to watch (JustWatch UK) · Updated June 2026