Holby City follows the staff of the fictional Holby City Hospital. The three leads were Adrian Edmonson as cardiothoracic surgeon Anton ‘Mac’ McCrory, Lisa Faulkner as ward sister (later nurse consultant) Faye Byrne, and John Michie as…
Main cast
- Anton ‘Mac’ McCroryAdrian Edmondson19–21, 23Main
- Faye ByrneLisa Faulkner14–19, 23Main
- Guy SelfJohn Michie13–17Main
Supporting cast
- Lily ‘Lofty’ SweetJaye Jacobs1–9, 23Supp
- Mickey TomlinsonMark Letheren6–12Supp
- Michael SpenceHari Dhillon9–20, 23Supp
- Sahira ShahLaila Rouass13–17Supp
Guest & voice
- Megan RobertsJanie Dee1Guest
- Rosie BattLucy-Jo Hudson16–17Guest
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About this cast
Holby City is a long-running BBC medical drama set at Holby City Hospital. It focuses on the personal and professional lives of its doctors, nurses, and support staff. The show premiered in 1999 and concluded in 2022 after 23 series.
FAQs
Who plays Anton ‘Mac’ McCrory in Holby City?
Adrian Edmondson plays cardiothoracic surgeon Anton ‘Mac’ McCrory. He joined as a main cast member from series 19.
How many series of Holby City are there?
Holby City ran for 23 series, from 1999 to 2022.
Is Holby City still on ITV?
No, Holby City was broadcast on BBC One. It ended in March 2022.
Who played Faye Byrne in Holby City?
Lisa Faulkner played ward sister Faye Byrne from series 14 to 19, and briefly returned in the final series 23.
Which actor played Guy Self?
John Michie played consultant neurosurgeon Guy Self from series 13 to 17.
Sources & where to watch: IMDb · Wikipedia · Where to watch (JustWatch UK) · Updated June 2026